Metribolone (Methyltrienolone) is the most powerful oral steroid ever produced. This drug is a close relative of trenbolone and differs only in 17-alpha alkylation. This modification makes it significantly more powerful than trenbolone. It is 120-300 times more powerful than methyltestosterone. This is the most powerful steroid available on the market, doses of 0.5-1mg are already enough for a powerful anabolic effect. Its activity is accompanied by strong toxicity, and this is what limits its use in laboratory conditions.

At present, methyltrienolone is the most affordable and high-quality steroid with a great anabolic effect for the occurrence of which requires 1 mg of the substance used. The versatility of the drug makes it an indispensable product in the field of sports pharmacology and everyday life and in the shortest possible time gives the desired result. Bribes the duration of active activity of the drug for a whole month from the moment of consumption. The main positive effects of this steroid are:

  • increase the volume of muscle fibers and muscle mass in the shortest possible time;
  • improving the shape of the muscle relief;
  • stabilization and acceleration of quality metabolism in the body;
  • increase in physical performance and strength.

The drug is classified by doctors as an anabolic and has a strong anabolic effect, however, overdose of the drug may have certain side effects, including:

  • obesity of the skin;
  • acne
  • accelerated hair growth in people regardless of their gender;
  • musculature in women;
  • increase in male hormones.

The drug has powerful androgenic properties and affects human sexual activity, the process of spermatogenesis in men, increased sexual desire in men and women, the duration of sexual intercourse and physical endurance at the time of active action of the drug, increase libido by affecting the central nervous system people, on their nerve endings, which enhance sexual desire. In the first minutes after taking the drug a person begins to feel blood flow to the genitals and pelvis, gradually increases over time, and reaches a peak that will occur within 1-2 hours after ingestion, while giving a quality and long-lasting effect for a long time .


Metribolone was first described in 1965. This is one of the most powerful anabolic steroids that has never been sold in pharmacies. This drug has only been used in laboratory studies. There were studies in the treatment of breast cancer in the 1960s and 1970s. It slowed down, and in some cases reversed, the process of tumor growth. Studies did not last long, due to the identified toxicity. In the mid-1970s, methyltrienolone was tested in animals to determine binding to androgen receptors. He was very suitable for this purpose. Its activity and resistance to blood binding proteins allowed it to easily become a reference substance. Due to its resistance to metabolism, methyltrienolone metabolites did not interfere with the results of most experiments.


Perhaps, the only good news is that metribolone does not aromatize or convert into estrogen.  Yet, it is extremely hepatotoxic, and it could be comparable to stacking 2 or 3 of the harshest oral steroids at the same time.  In fact, studies have shown that the experimental rats developed organ cancer when given this steroid at abusive levels.  Obviously, we can presume that this steroid has a 17-alpha methyl group attachment, which will lead to tremendous strain on the liver.

Furthermore, metribolone is also a 19nor steroid (just like trenbolone  or deca durabolin), and it has the ability to bind equally well in all tissues.  Hence, it is a great choice in universities studying androgen receptors.  As a matter of fact, it has been used since the 70’s for research in animals because it is so resistant to metabolism, meaning it doesn’t interfere with experimental results.  Interestingly, clinical research on humans is no longer an option due to its dangers.

How effective is Metribolone in bodybuilding?

Metribolone is a very effective steroid when it comes to increasing muscle mass. It is very powerful and has a very strong anabolic effect, which is why many athletes use it to improve their performance.

Metribolone is a synthetic anabolic steroid with a similar chemical structure to testosterone. It is used in the treatment of anemic patients and to stimulate red blood cell production. Metribolone has been found to be effective in bodybuilding as it increases nitrogen retention and protein synthesis, thus increasing muscle mass.

How effective is Metribolone in bodybuilding?

Also, the effectiveness of metribolone depends on the dosage, the duration of administration, and the type of exercise being done. The drug has been found to be more effective for short-term use than for long-term use.


Metribolone is not a product that should be used, so I do not recommend athletes or bodybuilders use it.  Those who are foolish enough to try it will run 0.5 milligrams (mgs) to 5mgs per day split dose.  Regarding the cycle duration, you should not exceed 3 to 4 weeks of use.

Metribolone can be taken in doses between 200 and 400 milligrams per day for 4-6 weeks.

It should not be taken by anyone with liver or kidney problems, heart diseases, or any other serious health issues. It is also contraindicated for women and children.

You should not exceed the dose of over 400 milligrams per day.

Also, for bodybuilders and athletes, the proper dosage would be around 400-600 mg per week.

Lastly, the proper dosage instructions for Metribolone are as follows:

  • One tablet should be taken daily, preferably in the morning with food.
  • The use of Metribolone is not recommended if you have a history of liver problems or if you are pregnant or breastfeeding.
  • It is advised that you consult your doctor before using this product.

The positive effects of using Metribolone

Many athletes began using metribolone to increase muscle mass and strength. The beneficial effects of this compound include:

  • Increased strength
  • Muscle hardness
  • Fat loss
  • Increased metabolism
  • Decreased cortisol levels
  • It has anabolic and androgenic properties.
  • It helps to increase muscle mass, stamina, and strength
  • It helps to increase bone density
  • It can be used as an anti-estrogen agent
  • It has a strong binding affinity to the androgen receptor (AR)
The positive effects of using Metribolone

Because its effects are not as dramatic as other compounds, it can also be used by those who want to experiment with a steroid for the first time.

Side Effects

As mentioned, metribolone does not aromatize into estrogen, but this can be a tricky issue.  For instance, Anadrol is another oral steroid that does not aromatize, but it still binds with estrogen.  In the meantime, metribolone will bind to progesterone receptors, as it is a progestin 19nor compound.  Thus, even though there is no aromatization to estrogen, you can still end up with progestin based gynecomastia (bitch tits) anyway.

Additionally, due to its strength, metribolone causes such androgenic sides as aggression, acne, and male pattern baldness.  If that weren’t enough, there are also the common steroid related issues, which are heart strain and suppression.

For women it will cause pronounced virilization symptoms, so female athletes should avoid metribolone at all cost.

Finally, liver damage can easily occur with metribolone, not just because it is 17-aa, but because it is highly resistant to hepatic metabolism.  Consequently, if you choose to run this compound, you need a good liver supporting supplement, and you should get blood work done both during and after usage.  Remember, it is easily the most liver toxic steroid in existence!  Therefore, a strong support supplement is crucial, and I recommend using a double dosage of N2Guard.